Jobs in Structural Biology and Related Fields

PhD Position in GPCR Biophysics at Prof. Georg Krainer lab

University of Graz, Austria

Application deadline: 01 Jul 2026

The Molecular Biophysics Group, led by Prof. Georg Krainer at the Institute of Molecular Biosciences (IMB), is seeking a highly motivated and talented PhD candidate to join our interdisciplinary research group at the University of Graz, Austria.

About the Position:

This role focuses on investigating GPCR signaling at the single-molecule level, integrating biochemical, biophysical, and single-molecule approaches. The main areas of research include:

• Expression and purification of GPCRs in yeast, insect, and mammalian cells
• Reconstitution of GPCRs into nanodiscs/liposomes, followed by functional characterization
• Single-molecule studies of GPCRs using confocal microscopy and TIRF
• Data analysis to characterize GPCR dynamics and interactions

Who Should Apply:

Candidates should have (or be near completion of) a Master’s degree in Biophysics, Biochemistry, Molecular Biology, Structural Biology, or a related field, ideally with experience in:

• Single-molecule fluorescence approaches (single-molecule FRET)
• Protein expression and purification
• Data analysis and programming

What We Offer:

• 3-year fixed-term contract (with the possibility of extension, 75% FTE, ca. 40,000 € gross/year)
• State-of-the-art facilities for single-molecule research, protein biochemistry and biophysics
• Collaborative research environment

How to Apply:

Send a single PDF to georg.krainer@uni-graz.at, including:

1. Cover letter (research interests & expertise)
2. CV & publication record
3. Contact info for 2–3 references

Applications are reviewed on a rolling basis until the position is filled.

Start Date: As soon as possible or upon mutual agreement.