Jobs in Structural Biology and Related Fields

A new positions, for a cryoEM/Biochemistry is now available at the Dr Juan Reguera Vidaechea

 

Postdoctoral Researcher – CHIKO ERC AdG
Position Overview
Position Title: Postdoctoral Researcher in Structural and Functional Virology
Project: CHIKO: Decoding the spatial and temporal sequence of Chikungunya virus infection (ERC Advanced Grant 2025)
Goal: Decode the structural and functional transitions of viral replication complexes during infection.
Supervisor: Juan Reguera (PI), AFMB, INSERM, CNRS/AMU, Marseille, France
Location: AFMB (Architecture et Fonction des Macromolécules Biologiques), Marseille, France
Contract Duration: 2 years (with possibility of extension)
Start Date: January 2027

 
They are seeking a highly motivated Postdoctoral Researcher to join the CHIKO project. The successful candidate will lead the structural and functional characterization of viral replication complexes at different stages of infection. This role offers the opportunity to contribute to groundbreaking research in viral replication, while gaining expertise in high-impact techniques, publishing in top-tier journals, and collaborating with international labs.

 

Key Responsibilities
•    Characterization of Viral Replication Complexes
o    Investigate the formation, evolution, and function of replication complexes during the viral life cycle.
o    Study the interactions between viral and host proteins with viral RNA and their role in replication.
•    Structural Analysis
o    Determine the high-resolution structures of replication complexes in various functional states using Cryo-Electron Microscopy.
o    Analyze structural data to elucidate mechanisms of viral replication and transcription.
•    Functional Studies
o    Assess the biochemical and enzymatic activities of replication complexes.
o    Explore the molecular determinants of viral RNA synthesis and processing.
•    Collaboration and Reporting
o    Work closely with team members and collaborators to integrate structural and functional findings.
o    Present results at project meetings, conferences, and in peer-reviewed publications.
 
Required Qualifications
Education
•    PhD in Structural Biology, Virology, Biochemistry, or a related field.
Technical Skills
•    Experience in macromolecular structure determination (e.g., Cryo-Electron Microscopy or related techniques).
•    Strong background in protein biochemistry and molecular biology. 
•    Familiarity with viral systems (preferably RNA viruses).
Soft Skills
•    Excellent problem-solving and analytical skills. 
•    Ability to work independently and collaboratively in a multidisciplinary team.
•    Strong communication skills .
 
Work Environment
•    Cutting-edge facilities: First-hand access to PBSIM (Marseille), Cryo-EM at Madrid CNB, and CRCM proteomics facility for comprehensive structural and interactomics analyses.
•    Collaborative network: Opportunity to work with leading experts in virology, structural biology, and interactomics.
•    Training opportunities: Participation in workshops, conferences, and advanced training to further develop expertise.
 
Application Process
Interested candidates should submit to juan.reguera@univ-amu.fr with CHIKO-PD1-application in the subject:
1.    CV (including publication list).
2.    Cover letter (1-2 pages) describing:
o    Research interests and relevance to CHIKO.
o    Experience with structural biology, virology, or related fields.
o    Career goals.
3.    Contact information for 2-3 references.
Deadline: Open until filled
Start Date: January 2027